Background:

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. Exportin 1 also regulates NFAT and AP-1.

Classification:

Primary antibody

Alternative names:

XPO1; CRM1; Exportin-1; Exp1; Chromosome region maintenance 1 protein homolog

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized acetyl-peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

Concentration:

1 mg/ml

Molecular weight:

123386

Applications:

WB, ELISA

Storage:

-20°C for one year

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