Background:

Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; CPN1 encodes the catalytic subunit. Mutations in CPN1 can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency.

Classification:

Primary antibody

Alternative names:

CPN1; ACBP; Carboxypeptidase N catalytic chain; CPN; Anaphylatoxin inactivator; Arginine carboxypeptidase; Carboxypeptidase N polypeptide 1; Carboxypeptidase N small subunit; Kininase-1; Lysine carbox

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458

Concentration:

1 mg/ml

Molecular weight:

52286

Applications:

WB, ELISA

Storage:

-20°C for one year

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