Background:

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. COX6C is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

Classification:

Primary antibody

Alternative names:

COX6C; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide VIc

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human COX6C. AA range:11-60

Concentration:

1 mg/ml

Molecular weight:

8781

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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