Background:

COL11A1 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in this gene is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for this gene.

Classification:

Primary antibody

Alternative names:

COL11A1; COLL6; Collagen alpha-1(XI) chain

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Collagen XI alpha1. AA range:581-630

Concentration:

1 mg/ml

Molecular weight:

181121

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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