Background:

CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein (CDC like kinase 1) phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for CLK1.

Classification:

Primary antibody

Alternative names:

CLK1; CLK; Dual specificity protein kinase CLK1; CDC-like kinase 1

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CLK1. AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

57205

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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