Background:

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full-length C1r chain and the cleaved B chain.

Classification:

Primary antibody

Alternative names:

C1R; Complement C1r subcomponent; Complement component 1 subcomponent r

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human C1R. AA range:414-463

Concentration:

1 mg/ml

Molecular weight:

80174

Applications:

WB, ELISA

Storage:

-20°C for one year

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