Background:

KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma v

Species reactivity:

Human; Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human c-Kit

Concentration:

1 mg/ml

Molecular weight:

109865

Applications:

IHC-p, WB

Storage:

-20°C for one year

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