Background:

Chromogranin A encoded by CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. CHGA product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for CHGA.

Classification:

Primary antibody

Alternative names:

CHGA; Chromogranin-A; CgA; Pituitary secretory protein I; SP-I

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Chr-A. AA range:311-360

Concentration:

1 mg/ml

Molecular weight:

50730

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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