Background:

Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by CDC40 (cell division cycle 40) is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.

Classification:

Primary antibody

Alternative names:

CDC40; EHB3; PRP17; PRPF17; Pre-mRNA-processing factor 17; Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CDC40. AA range:179-228

Concentration:

1 mg/ml

Molecular weight:

65521

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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