Background:

The protein encoded by CDC14A (cell division cycle 14A) is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of CDC14A results in several transcript variants encoding distinct isoforms.

Classification:

Primary antibody

Alternative names:

CDC14A; Dual specificity protein phosphatase CDC14A; CDC14 cell division cycle 14 homolog A

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human Cdc14a phosphatase.

Concentration:

1 mg/ml

Molecular weight:

66574

Applications:

WB, ELISA

Storage:

-20°C for one year

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