Background:

OPRPN (opiorphin prepropeptide) encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD88

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the N-terminal region of human C5AR1. AA range:1-50

Concentration:

1 mg/ml

Molecular weight:

38500

Applications:

WB, ELISA

Storage:

-20°C for one year

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