Background:

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

RHD; Blood group Rh(D) polypeptide; RHXIII; Rh polypeptide 2; RhPII; Rhesus D antigen; CD240D

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Blood group Rh(D) polypeptide at AA range: 161-210

Concentration:

1 mg/ml

Molecular weight:

45211

Applications:

WB, ELISA

Storage:

-20°C for one year

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