Background:

SIGLEC1 encodes a member of the immunoglobulin superfamily. The sialic acid binding Ig like lectin 1 is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.

Classification:

Primary antibody

Alternative names:

SIGLEC1; SN; Sialoadhesin; Sialic acid-binding Ig-like lectin 1; Siglec-1; CD169

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC1. AA range:1321-1370

Concentration:

1 mg/ml

Molecular weight:

182624

Applications:

WB, ELISA

Storage:

-20°C for one year

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