Background:

The poliovirus receptor encoded by PVR is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human PVR. AA range:81-130

Concentration:

1 mg/ml

Molecular weight:

45303

Applications:

WB, ELISA

Storage:

-20°C for one year

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