Background:

The protein encoded by this intronless gene THBD (thrombomodulin) is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in THBD are a cause of thromboembolic disease, also known as inherited thrombophilia.

Classification:

Primary antibody

Alternative names:

THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575

Concentration:

1 mg/ml

Molecular weight:

60329

Applications:

WB, ELISA

Storage:

-20°C for one year

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