Background:

The protein (syndecan 1) encoded by SDC1 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of SDC1 and encode the same protein.

Classification:

Primary antibody

Alternative names:

SDC1; SDC; Syndecan-1; SYND1; CD antigen CD138

Species reactivity:

Human;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SDC1. AA range:91-140

Concentration:

1 mg/ml

Molecular weight:

32462

Applications:

WB, ELISA

Storage:

-20°C for one year

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