Background:

JUP encodes a major cytoplasmic protein (junction plakoglobin) which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.

Classification:

Primary antibody

Alternative names:

JUP; CTNNG; DP3; Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Catenin-gamma. AA range:696-745

Concentration:

1 mg/ml

Molecular weight:

81630

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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