Background:

CTNNA1 encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein (catenin alpha 1) contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.

Classification:

Primary antibody

Alternative names:

CTNNA1; Catenin alpha-1; Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13; CTNNA2; CAPR; Catenin alpha-2; Alpha N-catenin; Alpha-catenin-related protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Catenin-alpha1. AA range:857-906

Concentration:

1 mg/ml

Molecular weight:

100071/105313

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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