Background:

CALB2 (calbindin 2) encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

Calretinin (CR) (29 kDa calbindin)

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from calbindin 2 at AA range: 191-240

Concentration:

1 mg/ml

Molecular weight:

31540

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

More info:

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