Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The calpain 9 encoded by CAPN9 is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for CAPN9.

Classification:

Primary antibody

Alternative names:

CAPN9; NCL4; Calpain-9; Digestive tract-specific calpain; New calpain 4; nCL-4; Protein CG36

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CAPN9. AA range:481-530

Concentration:

1 mg/ml

Molecular weight:

79097

Applications:

WB, ELISA

Storage:

-20°C for one year

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