Background:

CDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of CDH23 may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Classification:

Primary antibody

Alternative names:

CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110

Concentration:

1 mg/ml

Molecular weight:

369525

Applications:

IF, ELISA

Storage:

-20°C for one year

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