Background:

CDH18 encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for CDH18.

Classification:

Primary antibody

Alternative names:

CDH18; CDH14; Cadherin-18; Cadherin-14

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CDH18. AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

88073

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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