Background:

CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding different isoforms have been found for CABLES1.

Classification:

Primary antibody

Alternative names:

CABLES1; CABLES; CDK5 and ABL1 enzyme substrate 1; Interactor with CDK3 1; Ik3-1

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610

Concentration:

1 mg/ml

Molecular weight:

67599

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com