Background:

BUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine/threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

Classification:

Primary antibody

Alternative names:

BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BUB1B. AA range:341-390

Concentration:

1 mg/ml

Molecular weight:

119545

Applications:

WB, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

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