Background:

BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis-suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

BRMS1; Breast cancer metastasis-suppressor 1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

Concentration:

1 mg/ml

Molecular weight:

28461

Applications:

WB, ELISA

Storage:

-20°C for one year

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