Background:

ARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein (AT-rich interaction domain 4B) is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Classification:

Primary antibody

Alternative names:

ARID4B; BRCAA1; RBBP1L1; RBP1L1; SAP180; AT-rich interactive domain-containing protein 4B; ARID domain-containing protein 4B; 180 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p180; Bre

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BRCAA1. AA range:761-810

Concentration:

1 mg/ml

Molecular weight:

147809

Applications:

WB, ELISA

Storage:

-20°C for one year

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