Background:

Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by BDKRB1 (bradykinin receptor B1) is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for BDKRB1.

Classification:

Primary antibody

Alternative names:

BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250

Concentration:

1 mg/ml

Molecular weight:

40495

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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