Background:

BMP2 (bone morphogenetic protein 2) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of BMP2 causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

Classification:

Primary antibody

Alternative names:

BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Bone morphogenetic protein 2 at AA range: 341-390

Concentration:

1 mg/ml

Molecular weight:

44702

Applications:

IF, WB, IHC-p, ELISA

Storage:

-20°C for one year

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