Background:

BCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome 3. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from BCL2L12 . at AA range: 60-140

Concentration:

1 mg/ml

Molecular weight:

36821

Applications:

WB, ELISA

Storage:

-20°C for one year

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