Background:

ATP7B (ATPase copper transporting beta) is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in ATP7B have been associated with Wilson disease (WD).

Classification:

Primary antibody

Alternative names:

ATP7B; PWD; WC1; WND; Copper-transporting ATPase 2; Copper pump 2; Wilson disease-associated protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ATP7B. AA range:161-210

Concentration:

1 mg/ml

Molecular weight:

157334

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com