Background:

The protein encoded by ARR3 is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function.

Classification:

Primary antibody

Alternative names:

ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388

Concentration:

1 mg/ml

Molecular weight:

42778

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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