Background:

The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. ARFGAP3 was originally known as ARFGAP1, but that is now the name of a related but different gene.

Classification:

Primary antibody

Alternative names:

ARFGAP3; ARFGAP1; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from ARF GAP3 . at AA range: 280-360

Concentration:

1 mg/ml

Molecular weight:

56928

Applications:

WB, ELISA

Storage:

-20°C for one year

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