Background:

AMPD3 encodes a member of the AMP deaminase gene family. The adenosine monophosphate deaminase 3 is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Classification:

Primary antibody

Alternative names:

AMPD3; AMP deaminase 3; AMP deaminase isoform E; Erythrocyte AMP deaminase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from AMPD3 . at AA range: 280-360

Concentration:

1 mg/ml

Molecular weight:

88812

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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