Background:

AK1 encodes an adenylate kinase enzyme involved in energy metabolism and homeostasis of cellular adenine nucleotide ratios in different intracellular compartments. AK1 is highly expressed in skeletal muscle, brain and erythrocytes. Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

AK1; Adenylate kinase isoenzyme 1; AK 1; ATP-AMP transphosphorylase 1; Myokinase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human KAD1 . AA range:101-150

Concentration:

1 mg/ml

Molecular weight:

21635

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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