Background:

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. ADNP encodes activity dependent neuroprotector homeobox that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described.

Classification:

Primary antibody

Alternative names:

ADNP; ADNP1; KIAA0784; Activity-dependent neuroprotector homeobox protein; Activity-dependent neuroprotective protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ADNP. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

123563

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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