Background:

ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18) encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may regulate hemostatic balance and function as a tumor suppressor. Mutations in ADAMTS18 may be associated with microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) and cone-rod dystrophy in human patients.

Classification:

Primary antibody

Alternative names:

ADAMTS18; ADAMTS21; A disintegrin and metalloproteinase with thrombospondin motifs 18; ADAM-TS 18; ADAM-TS18; ADAMTS-18

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from ADAMTS-18 . at AA range: 1030-1110

Concentration:

1 mg/ml

Molecular weight:

135141

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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