Background:

ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by ADAMTS12 contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

Classification:

Primary antibody

Alternative names:

ADAMTS12; A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS 12; ADAM-TS12; ADAMTS-12

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from ADAMTS-12 . at AA range: 1100-1180

Concentration:

1 mg/ml

Molecular weight:

177545

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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