Background:

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).

Classification:

Primary antibody

Alternative names:

ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250

Concentration:

1 mg/ml

Molecular weight:

54871

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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