Background:

ACVR1B encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in ACVR1B are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

ACVR1B; ACVRLK4; ALK4; Activin receptor type-1B; Activin receptor type IB; ACTR-IB; Activin receptor-like kinase 4; ALK-4; Serine/threonine-protein kinase receptor R2; SKR2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ACV1B. AA range:73-122

Concentration:

1 mg/ml

Molecular weight:

56807

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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