Background:

NCKX1, also designated solute carrier family 24, member 1 (SLC24A1) or sodium/calcium/potassium exchanger 1, belongs to a family of potassium-dependent sodium/calcium exchangers. Members of this group of proteins contain two large hydrophilic loops and two sets of multiple transmembrane-spanning segments. One intron in the 5' untranslated region and eight within the coding region of the NCKX1 gene have been identified; exon length varies from 54 to 2,037 bp. Human NCKX1 encodes a protein of 1,081 amino acids that shows 64% overall identity with the cow protein. The two sets of presumed transmembrane domains and their short connecting loops show 94% identity with that of the cow, while the extracellular loop at the amino terminus is only 59% identical.

Specificity:

SLC24A1 polyclonal antibody detects endogenous levels of SLC24A1 protein.

Alternative names:

Sodium/potassium/calcium exchanger 1; Na(+)/K(+)/Ca(2+)-exchange protein 1; Retinal rod Na-Ca+K exchanger; Solute carrier family 24 member 1; KIAA0702; NCKX1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 198-243 of Human SLC24A1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 121 kDa

Applications:

WB ICC

Usage:

WB: 1:500~1:1000 ICC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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