Background:

Galactose kinase (GALK1), also often designated galactokinase, is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism. Defects in the gene encoding for galactose kinase, GALK1, can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population it can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye.

Specificity:

GALK1 polyclonal antibody detects endogenous levels of GALK1 protein.

Alternative names:

Galactokinase; Galactose kinase; GALK1; GALK

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 4-49 of Human GALK1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 42 kDa

Applications:

WB IHC ICC

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200 ICC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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