Background:

The StARD (steroidogenic acute regulatory protein-related lipid transfer (START) domain containing) family of proteins is comprised of fifteen different members. All members contain the characteristic START domain and are believed to play key roles in the metabolism and transport of lipids. The StARD proteins are grouped into six subfamilies based on their START domain sequences. PC-TP (StARD2), StARD7, StARD10 and GPBP (StARD11) constitute one subfamily, namely the STARD2/PCTP group. StARD10, also known as PCTP2, PCTPL, NY-CO-28, CGI-52 or SDCCAG28, is widely expressed and functions in phospholipid transfer, binding to phosphatidylcholine and phosphatidylethanolamine. StARD10 can be found in sperm flagellum, potentially functioning as an enzyme involved in energy metabolism, and its expression is developmentally regulated in testis and mammary glands. StARD10 activity can be inhibited via phosphorylation by casein kinase II.

Specificity:

STARD10 polyclonal antibody detects endogenous levels of STARD10 protein.

Alternative names:

PCTP-like protein; PCTP-L; Antigen NY-CO-28; START domain-containing protein 10; StARD10; Serologically defined colon cancer antigen 28; StAR-related lipid transfer protein 10; SDCCAG28; ORF Names: CGI-52; CGI52

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 105-150 of Human STARD10.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 35 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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