Background:

APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A), also known as PHO1 or ARP3 or PHRBN is a 199 amino acid protein that belongs to the cytidine deaminase family. Expressed in keratinocytes, as well as in peripherical leukocytes, APOBEC3A may be implicated in cell growth and cell cycle control. The gene encoding APOBEC3A is one of seven related genes which map to a cluster on chromosome 22 and are thought to play a role in tumor transformation and metastasis, as well as in host-associated antiviral activity. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2.

Specificity:

PHO1 polyclonal antibody detects endogenous levels of PHO1 protein.

Alternative names:

DNA dC->dU-editing enzyme APOBEC-3A; A3A; Phorbolin-1; APOBEC3A; Phorbolin 1; Phorbolin1; PHO-1

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 67-112 of Human PHO1.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 23 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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