Background:

Members of the Neurexophilin family are neuropeptide-like glycoproteins that undergo proteolytic processing after synthesis. As secreted proteins, Neurexophilins are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin Iα (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. Neurexophilins contain five common domains including a variable N-terminal domain, a highly conserved N-glycosylated central domain, a short linker region and a cysteine-rich conserved C-terminal domain. Neurexophilin-4, also known as NXPH4 or NPH4, is a 308 amino acid secreted protein belonging to the neurexophilin family. Neurexophilin-4 is expressed in brain, spleen and testis.

Specificity:

Neurexophilin-4 (P248) polyclonal antibody detects endogenous levels of Neurexophilin-4 protein.

Alternative names:

Neurexophilin 4; NXPH4; NPH4; UNQ1928/PRO4403

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 221-270 of Human Neurexophilin-4.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 33 kDa

Applications:

IHC

Usage:

IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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