Background:

Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role,such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively xpressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.

Specificity:

Fgl2 (V38) polyclonal antibody detects endogenous levels of Fgl2 protein.

Alternative names:

Fibroleukin; Fibrinogen-like protein 2; pT49; FGL2

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 6-60 of Human Fgl2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 50 kDa

Applications:

WB

Usage:

WB: 1:500~1:1000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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