Background:

The bombesin receptor family includes the gastrin-releasing peptide (GRPR) and neuromedin B (NMBR) receptors. Both receptors are expressed in various brain regions and in the digestive tract. NMBR belongs to the G proteincoupled receptor 1 family. The gene encoding NMBR protein maps to chromosome 6q21-qter. NMBR, an integral membrane protein, binds neuromedin B, a mitogen and growth factor for gastrointestinal epithelial tissue and normal and neoplastic lung.

Specificity:

NMBR (L264) polyclonal antibody detects endogenous levels of NMBR protein.

Alternative names:

NMB-R; Neuromedin-B-preferring bombesin receptor; NMBR

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 235-280 of Human NMBR.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 43 kDa

Applications:

IHC IF

Usage:

IHC: 1:50~1:200 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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