Background:

Cytochrome c oxidase subunit VIc (COX6c), also designated oxidative phosphorylation (OxPhos) complex IV, subunit VIc, is one of the structural subunits of the mitochondrial respiratory chain encoded by nuclear genes. Cytochrome c oxidase is a hetero-oligomeric enzyme composed of 13 subunits localized to the mitochondrial inner membrane and is the terminal enzyme complex of the electron transport chain. Complex IV catalyzes the reduction of molecular oxygen to water. The energy released is used to transport protons across the mitochondrial inner membrane.

Specificity:

COX6c (R40) polyclonal antibody detects endogenous levels of COX6c protein.

Alternative names:

COX 6C; Cox6c; Cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase subunit 6C;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 11-60 of Human COX6c.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 9 kDa

Applications:

IHC

Usage:

IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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