Background:

C/EBP family members include C/EBP α, C/EBP β, C/EBP γ, C/EBP δ, C/EBP ε and C/EBP ζ, all of which are capable of forming homodimers or heterodimers with each other. C/EBP ζ, also known as CBF2, NOC1, CHOP10 (C/EBP homologous protein 10), GADD153 (growth arrest and DNA damage-inducible gene 153) or HSPCBF, is a ubiquitously expressed 1,054 amino acid protein that localizes to the nucleus and regulates transcription. More specifically, C/EBP ζ is believed to play a role regulating the expression of CRP (C-reactive protein). Unlike most C/EBP dimers, C/EBP ζ-containing dimers do not bind the classical C/EBP-binding consensus sequence. Rather, C/EBP ζ-containing dimers must associate with RBP-Jκ (another transcription factor) in order to accomplish binding to the C/EBP site.

Specificity:

C/EBP ζ (D24) polyclonal antibody detects endogenous levels of C/EBP ζ protein.

Alternative names:

CBF2; CCAAT binding factor; CCAAT box binding transcription factor; CCAAT/enhancer binding protein zeta; Cebpz; HSPCBF; CBF;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to the N-terminus of Human C/EBP ζ.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~121 kDa

Applications:

WB IHC

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com