Background:

Alpha-2C adrenergic receptors (α2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. α2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. α2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.

Specificity:

AR α2C (R369) polyclonal antibody detects endogenous levels of AR α2C protein.

Alternative names:

Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2CAR; ADRA2C; ADRA2L2; ADRA2RL2; α-2C adrenergic receptor; α-2 adrenergic receptor subtype C4; α-2C adrenoreceptor; α-2C adrenoceptor; α-2CAR; ARα-2C; AR α2C; ARα2C; ARα 2C;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Synthetic peptide, corresponding to amino acids 340-390 of Human AR-α2C.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 70 kDa

Applications:

WB IHC IF

Usage:

WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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