Background:

QIK (Qin-induced kinase) is a serine/threonine-protein kinase that belongs to the AMPK/SNF1 kinase family. Also designated SIK2 (SNF1-like kinase 2), QIK is one of twelve human kinases (NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK) related to AMPK. QIK is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. In vitro kinase tests demonstrate that QIK is capable of autophosphorylation. Elevated levels of QIK transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.

Specificity:

SIK2 polyclonal antibody detects endogenous levels of SIK2 protein.

Alternative names:

QIK; SIK-2; SNF1LK2; LOH11CR1I;

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human SIK2.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 129 kDa

Applications:

WB

Usage:

WB 1:500 - 1:2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com